论文共读
May
Early?enteral?feeding?onesophagealcancerpatientsafteresophagealresectionandreconstruction.
BACKGROUND背景
Inpatientsunderesophagectomy,earlypostoperativeoralfeedinghastraditionallybeencontraindicatedtominimizetheriskofanastomoticleaks.Becauseearlyoralfeedingpreservestheintegrityandfunctionofgutmucosa,theaimofthisstudywastoinvestigatetheimpactofpostoperativeearlyoralfeedingonesophagectomy.
对于食管癌患者手术后传统上禁忌术后早期经口进食,以最大程度地减少吻合口漏的风险。由于早期经口进食有助于维护肠道粘膜的完整性及其功能,因此本研究的目的是研究术后早期经口进食对食管切除术后的影响。
METHODS方法
BetweenOctandJan,41consecutivepatientswithesophagealcarcinoma(stagesI-III),whohadundergoneminimallyinvasiveIvor-Lewissurgery,wereenrolledinthisstudy.Thepatientswererandomlyarrangedintotheearlyoralfeeding(EOF)group(21cases)andthesimpletubefeeding(STF)group(20cases).Thenutritionalgoalforbothgroupswas25kcal/(kg·day).ThepatientsintheEOFgroupweretube-fedwithenteralnutritionandorallyfedwith5%glucoseinnormalsalineduringthefirst4postoperativedays,afterthatthepatientswereplacedonaliquiddiet.ThepatientsintheSTFgroupwerepostoperativelytube-fedwithenteralnutritionfor7daysbeforebeingswitchedtoliquiddiet.Thelengthofthepostoperativehospitalstay,rateofperioperative